Relation between Chromium, Iron and Copper with Gestational Diabetes in Zabol, Iran
Published: November 1, 2018 | DOI: https://doi.org/10.7860/JCDR/2018/35574.12268
Reza Didedar, Tayebeh Rabaninia, Babak Barmaki, Somayeh Dahmardeh, Fahimeh Nori, Somaye Bagheri, Fardin Ali Malayeri
1. Faculty of Medicine, Department of Clinical Biochemistry, Zabol University of Medical Sciences, Zabol, Iran.
2. M.Sc of Genetics, Department of Research and Technology, University of Medical Sciences, Zabol, Iran.
3. Assistant Professor, Department of Clinical Physiology, Faculty of Medicine, Zabol University of Medical Sciences, Zabol, Iran.
4. MSc of Physical Chemistry, Department of Medicinal Chemistry, Faculty of Pharmacy, Zabol University of Medical Sciences, Zabol, Iran.
5. Lecturers, Department Biostatisics and Epidemiology, School of Health, Zabol University of Medical Sciences, Zabol, Iran.
6. M.Sc of Biochemistry, Department of Biology, Payaam-e-Noor University of Yazd, Taft Center, Iran.
7. Assistant Professor, Department of Clinical Biochemistery, Zabol Medical University, Zabol, Iran.
Correspondence
Dr. Fardin Ali Malayeri,
Assistant Professor, Department of Clinical Biochemistery, Faculty of Medicine, Medical University of Zabol, Zabol, Iran.
E-mail: Falimalayeri@gmail.com
Introduction: Diabetes is one of the most common chronic diseases. Gestational Diabetes Mellitus (GDM) is a type of diabetes that starts during pregnancy.
Aim: To study the levels of chromium, iron, and copper in women with GDM compared with non-diabetic pregnant women.
Materials and Methods: In this case-control study that was performed in Amir Al Momenin Hospital (Zabol-IRAN) in 2016 (from may to October). Sixty pregnant women with GDM were included in the study group and 60 non-diabetic pregnant women were included in the control group. Seven millilitres of blood was taken from the study participants for serum separation. For measuring the levels of chromium, iron, and copper Atomic Absorption Spectrometry was used. Data analysis was performed by Student’s t-test using the Statistical Package for the Social Sciences (SPSS) software version 16.
Results: Serum levels of chromium (7.76±2.83 vs 6.52±2.74 ng/dL), iron (0.60±0.10 vs 0.55±0.14 µg/dL) and copper (0.97±0.22 vs 0.83±0.22 µg/dL) were lower in the case group compared with the control group. Their difference was not statistically significant (p>0.05). The average age of participitants was 34.4±8.01 years. There was no significant difference in age between groups.
Conclusion: The present research showed that levels of Chromium, Iron and Copper in diabetic pregnant women were lower than that of non-diabetic pregnant women; but, these values did not had statistically significant difference.
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